Work Package 1 – Project Management
Work Package 1 will set up a clear organisational structure that guarantees efficient project management, smooth scientific coordination, data- and risk management and adequate legal coordination.
- Implementation of efficient management and support structures
- Scientific coordination, quality assurance & risk management
- Legal & Contractual settings
- Reporting, financial management & controlling
Work Package 2 – Development of a long-term calibration-free multi-metabolite sensor
Work Package 2 defines clear system requirements based on user needs, monitors the development and performance of the device and participates in prototype assembly.
- System specification definition
- Design
- Electronic mock development for interaction with partners
- System development and integration
- In-vitro performance testing
- Sensort algorithm development
- Prototype assemblies
Work Package 3 – Fully implantable physiologic high-precision insulin delivery system multisensing device
Work package 3’s responsibilities ensure the full development of the fully implantable physiologic high-precision insulin delivery system, from design to integration and test.
- Silicon micropump with integrated safety valve
- System development of implant mechanics and fluidics
- System development of electronics and firmware
- Investigation and development of self-sensing capabilities System integration and assembly
- Outside the body control system
- Dual-way interaction between safety & MEMS
Work Package 4 – Multi-Metabolite Data Science
Work Package 4 is responsible for the development of the MM Data Science behind the device through data analysis MM modelling and simulation and control and safety procedures development.
- MM time series analysis
- MM modelling
- IP & MM simulator
- Controller design
- Safety development
Work Package 5 – Unobtrusive ITD management: human factors
Work Package 5 will define concrete goals for unobtrusive diabetes management, identify human factors impacting the user experience, assess system performance and clinical outcomes and develop online educational tools.
- Initial qualitative and quantitative interviews in different user population subgroups
- Creating an ongoing feedback loop with potential user population
- Development of a readiness index for unobtrusive diabetes management
- Assessment of patient-reported outcomes
- Development of an online training program
Work Package 6 – Clinical/animal validation of system components and in silico system validation
Work Package 6 assesses the safety and accuracy of system components through clinical trials.
- Ethical approval of study protocol for the assessment of safety and accuracy of the implanted MM sensor
- Safety and efficacy on glucose levels of the multi-metabolite sensing and IP insulin infusion control algorithm
Work Package 7 – Innovation management: Communication, Dissemination, Exploitation
Work Package 7 ensures the consistent management of communication, dissemination, exploitation and outreach activities of the project, and their coordination with the project partners.
- Project Communication
- Dissemination of project results and stakeholder outreach
- Project exploitation and IP management
Work Package 8 – Portfolio activities
Work package 8 supports the project’s transition towards market dynamics and further exploitation opportunities through the definition of synergy opportunities.
- Collaboration with other projects
- EIC meetings
- Collaboration Meetings
- Outreach events